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KMID : 0383820130750030111
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Tuberculosis and Respiratory Diseases
2013 Volume.75 No. 3 p.111 ~ p.115
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Multiple Cancers in a Patient with Systemic Sclerosis and Aggravated Interstitial Lung Disease by Chemotherapy
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Park Chan-Kwon
Lee Seok-Jong
Cho Hyung-Jun
Lee Kyeong-Soo
Kim Sung-Jun
Cho Gu-Min
Lee Ha-Ni
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Abstract
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Although the relationship between malignancy risk with systemic sclerosis (SSc) has been inconclusive, there are some previous studies for a positive correlation. Most patients with SSc have some degree of lung parenchymal involvement in the form of interstitial thickening and fibrosis. Interstitial lung disease is the most common pulmonary manifestation of SSc. Interstitial lung disease following chemotherapy (5-fluorouracil, leucovorin, and oxaliplatin [FOLFOX]) is an uncommon life-threatening complication and it is induced by oxaliplatin. We report a case of multiple cancers in a patient with SSc and aggravated interstitial lung disease by chemotherapy.
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KEYWORD
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Scleroderma, Systemic, Lung Neoplasms, Lung Diseases, Interstitial
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